Incidence and Severity of Postoperative Sore Throat And Intubation Response by Using Different Devices for Endotracheal Intubation

King Saud University

Status: Completed

Conditions: Endotracheal Intubation; Pharyngitis; Pain

Treatments: Device: Endotracheal intubation

Study type: Interventional

Funder types: Other

Identifiers

NCT02848365

E-11-398

Details and patient eligibility

About

Postoperative sore throat (POST) is a common problem following the use of endotracheal intubation during general anaesthesia. It leads to dissatisfaction and discomfort after surgery and can delay a patient's return to normal routine activities. POST has been rated by patients as the eighth most adverse effect in the postoperative period. The incidence of sore throat after endotracheal intubation varies from 14.4-90%. Laryngoscopy and tracheal intubation also leads to hemodynamic stress response. The response can be deleterious in patient with or without cardiac disease. It is related to the degree of manipulation of the airway during endotracheal intubation and has been studied during intubation for some equipment used for endotracheal intubation

Enrollment: 420 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• After signing of the informed consent,
• ASA physical status I and II
• Mallampati class 1& 2,
• BMI < 35,
• Undergoing elective surgical procedures (not exceeding two hours in duration) requiring ET intubation

Exclusion criteria

• Patients undergoing day case,
• bariatric, cardiac, nasal, oral or head & neck surgeries,
• requiring placement of throat pack or nasogastric/ orogastric tube,
• patients assigned to rapid sequence induction,
• hoarseness,
• patients with anticipated difficult intubation,
• history of recent upper respiratory tract infection,
• history of difficult intubation
• psychiatric disorders hindering proper evaluation,
• use of steroids (oral or inhalational) or non-steroidal anti-inflammatory drugs within one week of surgery or previous surgery within last two weeks

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

---

420 participants in 6 patient groups

Glidescope

Active Comparator group

Treatment:

Device: Endotracheal intubation

Macintosh laryngoscope

Active Comparator group

Treatment:

Device: Endotracheal intubation

Bonfill's rigid scope

Active Comparator group

Treatment:

Device: Endotracheal intubation

Air traq

Active Comparator group

Treatment:

Device: Endotracheal intubation

C -Mac scope

Active Comparator group

Treatment:

Device: Endotracheal intubation

flexible fiberoptic scope

Active Comparator group

Treatment:

Device: Endotracheal intubation