ClinicalTrials.Veeva

Menu

Incidence of Caries in Smoking and Smokeless Tobacco (ICSSLT)

P

Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre

Status

Completed

Conditions

DENTAL CARIES

Study type

Observational

Funder types

Other

Identifiers

NCT02767050
PMVIDS&RC/IEC/OMR/PR/0046-15

Details and patient eligibility

About

The following observational study evaluates incidence of caries in smoking and smokeless tobacco based on habit history by clinical examination and DMFT index.

Full description

Dental caries is an irreversible microbial disease of the calcified tissues of the teeth, characterized by demineralization of the inorganic portion and destruction of the organic substance of the tooth, which often leads to cavitation. It is a complex and dynamic process where a multitude of factors influence and initiate the progression of disease. There are practically no geographic areas in the world whose inhabitants do not exhibit some evidence of dental caries. It affects persons of both genders in all races, all socioeconomic strata and every age group. Likewise, there is strong evidence that tobacco use has numerous negative effects on oral health, for example staining of teeth, dental restoration, development of oral diseases. A biologically reasonable explanation for an association between chewing tobacco use and dental caries may be the presence of higher levels of fermentable sugars in chewing tobacco products which can stimulate the growth of carcinogenic bacteria. The decreased buffering effect possible lower pH of smokers saliva and higher number of lactobacilli and streptococcus mutans group may indicate an increased susceptibility to caries in smokers. On the other hand, there are researches which conclude that presence of extrinsic tobacco stains appear to provide a protective effect from caries.

Enrollment

613 patients

Sex

All

Ages

15 to 100 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Patients who are willing for the study.
  • A positive history of dental caries in smokers and smokeless tobacco.
  • Patients with caries not under any treatment of the same.

Exclusion criteria

  • Unwilling patients who do not want to be a part of the study.
  • Patient with fluorosis.

Trial design

613 participants in 3 patient groups

GROUP 1: CONTROL GROUPS
Description:
Patients with no habit history of tobacco are included in group 1.
GROUP 2: SMOKING TOBACCO
Description:
Patients with a history of tobacco consumption in the form of smoking.
GROUP 3: SMOKELESS TOBACCO
Description:
Patients with a history of tobacco consumption in the form of chewing.

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems