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Incidence of Complications Associated With Anesthesia in Obesity Parturient Undergoing Cesarean Delivery

M

Mahidol University

Status

Completed

Conditions

Cesarean Section Complications
Anesthesia Complication
Obesity, Morbid

Treatments

Procedure: Anesthesia; general or regional

Study type

Observational

Funder types

Other

Identifiers

NCT04657692
Si 125/2020 (Other Identifier)
873/2562 (EC2)

Details and patient eligibility

About

The incidence of obesity parturient has been increasing worldwide. There was a report revealing one third of pregnant women in United state considered obesity.

Obesity is associated with increased in maternal and neonatal complications. Also, there was an increasing in the rate of cesarean delivery. Anesthetic management of the obese parturient is differ from non-obese parturients. There were higher risk of difficult intubation, failed intubation, pulmonary aspiration and difficult regional anesthesia such as spinal anesthesia or epidural catheter placement comparing with non-obese parturient.

The aim of the study is to report complication associated with anesthesia in obese patients undergoing cesarean delivery in Single University hospital, Bangkok, THAILAND.

Full description

The incidence of obesity parturient has been increasing worldwide. There was a report revealing one third of pregnant women in United state considered obesity.

Obesity is associated with increased in maternal and neonatal complications. Also, there was an increasing in the rate of cesarean delivery. Anesthetic management of the obese parturient is differ from non-obese parturients. There were higher risk of difficult intubation and difficult regional anesthesia such as spinal anesthesia or epidural catheter placement comparing with non-obese parturient.

WHO categorised obesity into 3 classification; grade 1: BMI 30-34.9 kg/m2, grade 2: BMI 35-39.9 kg/m2, grade 3: BMI > 40 kg/m2. This study emphasised in grade 3 obese pregnant women (BMI>40 kg/m2) undergoing cesarean delivery that were at risk of increasing in anesthetic complications such as airway complications as well as complications derived from regional anesthesia eg. high spinal block, failed spinal block etc.

Therefore, the primary objective of the study is to report complication associated with anesthesia in obese patients undergoing cesarean delivery in Single University hospital, Bangkok, THAILAND. The secondary objectives rate of postpartum haemorrhage, rate of hysterectomy and neonatal outcomes.

Enrollment

527 patients

Sex

Female

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Pregnant women BMI>,= 40 kg/m2 underwent cesarean delivery

Exclusion criteria

  • Patients with gestational age <,= 24 weeks
  • Patients with death fetus in Utero
  • Multiple gestation
  • Patients with intrapelvic cavity pathology eg. myoma uteri
  • Patients with abnormal placentation
  • Patients with polyhydramnios

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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