Incidence of Postoperative Diaphragmatic Dysfunction in Pregnant Women With Preeclampsia

Cairo University (CU)

Status: Enrolling

Conditions: Preecalmpsia

Study type: Observational

Funder types: Other

Identifiers

NCT07443345

N-62-2026

Details and patient eligibility

About

Preeclampsia with severe features remains a leading contributor to maternal morbidity and mortality, particularly in low- and middle-income countries. It is defined by hypertension and involvement of multiple organ systems, including renal, hepatic, hematologic, and neurologic pathways. The interplay of endothelial dysfunction, capillary leakage, and disrupted fluid balance in these patients increases their susceptibility to perioperative pulmonary complications. Although respiratory complications in preeclampsia are clinically significant, the true incidence of postoperative diaphragmatic dysfunction in women with severe disease is not well established. Existing literature largely emphasizes general respiratory failure, pulmonary edema, or the need for mechanical ventilation, rather than specifically evaluating diaphragmatic performance with objective methods such as ultrasound. The current study sought to determine the incidence and identify risk factors for postoperative diaphragmatic dysfunction in women with severe preeclampsia following cesarean delivery.

Enrollment: 52 estimated patients

Sex: Female

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with severe preeclampsia undergoing cesarean section
• Gestational age > 32 weeks

Exclusion criteria

• • Age < 20 years.

  • Diabetic
  • Patients with neuromuscular diseases.
  • Patient refusal.
  • Contraindications to magnesium sulphate administration
  • Inability to obtain adequate ultrasound views

Trial design

52 participants in 1 patient group

Preeclampsia with severe features

Description:

diaphragmatic excursion evaluation