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Incidental Cancer in Familial Adenomatous Polyposis

D

Dr. Ersin Arslan Education and Training Hospital

Status

Completed

Conditions

Cancer

Study type

Observational

Funder types

Other

Identifiers

NCT05171426
2018/16-20

Details and patient eligibility

About

Colectomy is life-saving in patients with familial adenomatous polyposis (FAP) because cancer development is inevitable in individuals with this disease. In this study, we aimed to determine the incidence of incidental malignancy in surgical specimens from patients who underwent colectomy for FAP. Prophylactic colectomy should be performed in patients with FAP, as colorectal cancer transformation is inevitable in these individuals. The possibility of incidental cancer identified via histopathological analysis of colectomy specimens should be kept in mind in these patients.

Full description

Colectomy is life-saving in patients with familial adenomatous polyposis (FAP) because cancer development is inevitable in individuals with this disease. In this study, we aimed to determine the incidence of incidental malignancy in surgical specimens from patients who underwent colectomy for FAP. The files of patients diagnosed with FAP who underwent surgery in our clinic between 2010 and 2020 were retrospectively reviewed. Definitive surgery was performed in patients with histopathological malignancy identified in colonoscopic biopsies in the preoperative period, while prophylactic surgery was performed in patients without malignancy. The incidence of incidental malignancy in histopathological specimens from patients who underwent prophylactic colectomy was determined. Prophylactic colectomy should be performed in patients with FAP, as colorectal cancer transformation is inevitable in these individuals. The possibility of incidental cancer identified via histopathological analysis of colectomy specimens should be kept in mind in these patients.

Enrollment

55 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • diagnosed with Familial Adenomatous Polyposis

Exclusion criteria

  • did not receive surgical treatment
  • data deficiencies

Trial design

55 participants in 1 patient group

incidental cancer
Description:
familial adenomatous polyposis with incidental cancer

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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