Incidental Finding of Gastrointestinal Stromal Tumors (GISTs) During Laparoscopic Sleeve Gastrectomy, How to Deal? How Much Safety Margin

Bassem Mohamed Sieda

Status: Unknown

Conditions: Excision Margin

Treatments: Procedure: Laparoscopic sleeve gastrectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT04344847

0000-0002-9590

Details and patient eligibility

About

LSG is thought to be the best choice for obese patients with conincidental GISTs, as a tumour can be resected along with resecting the stomach within the same procedure. The primary endpoint is that, how much does GIST suppose to be far from a staple line to do safe laparoscopic sleeve gastrectomy

Full description

The incidence of unsuspected GIST in LSG specimens in our series was high in comparison to cases reported in the literature.

GISTs could be safely removed laparoscopically during LSG surgery with negative microscopic resection margins, with 1-2cm safety margin. Margins less than 1cm, high mitotic rate are adverse prognostic factors.

Examining the whole stomach before resection is mandatory and can easily be done during LSG, GIST can be removed safely with LSG

Enrollment: 338 estimated patients

Sex: All

Ages: 21 to 42 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

All morbid obese patients with BMI more than 35

Exclusion criteria

• previous gastric surgery
• patients with hiatus hernia
• age under 21 years

Trial design

338 participants in 1 patient group

coincidental GIST during LSG patients

Other group

Description:

With institutional review board approval from Zagazig University Hospitals 338. A double-centre prospective study was conducted on prospectively collected data of all morbidly. 17 patients in Zagazig University Hospitals, Faculty of Medicine, Egypt and 321 patients done in bariatric surgery excellence unit in a tertiary hospital in Riyadh-KSA.

Treatment:

Procedure: Laparoscopic sleeve gastrectomy