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Incontinence and MRI Results in Children with Cerebral Palsy

G

Ghent University Hospital (UZ)

Status

Completed

Conditions

Lower Urinary Tract Symptoms
Cerebral Palsy

Treatments

Other: Vancouver symptom score for dysfunctional elimination syndroms
Other: Magnetic resonance imaging

Study type

Observational

Funder types

Other

Identifiers

NCT05060211
B6702021000735

Details and patient eligibility

About

More than 50 % of children and adults with cerebral palsy experience lower urinary tract symptoms (LUTS). This can negatively influence quality of life of the child and the total social environment.

Previous research demonstrated that the brain lesion, characteristic for cerebral palsy (CP), is a prognostic factor for the functional abilities of a child with CP. Previous research within our department demonstrated functional impairment as a risk factor for incontinence. This demonstrates an indirect connection between the brain lesion and incontinence of a child with CP. However, this connection isn't alway correct as some children with high functionality also demonstrate incontinence.

As bladder control is also regulated by higher brain centers, the present study wants to investigate a direct connection between the brain lesion of the child, visible by means of MRI, and the incontinence status of the child. .

Full description

The current study is a cross-sectional observational study in which a correlation is investigated between known anatomical MRI results and the continence status of a child with CP.

Although neuroimaging isn't seen as a requirement for the definition and diagnosis of CP2, MRI imaging is often part of diagnostic evaluation. The Surveillance of Cerebral Palsy in Europe (SCPE) working group composed the MRI classification system or MRICS classifying neuroimaging results in maldevelopments, predominant white matter injury, predominant grey matter injury, miscellaneous and normal. These results will be correlated with results of the validated Vancouver symptoms score for dysfunctional elimination syndrome.

Enrollment

125 patients

Sex

All

Ages

5 to 12 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Diagnosis of cerebral palsy
  • MRI investigation in history
  • Dutch or French speaking child and parent

Exclusion criteria

  • No MRI investigation in history
  • Child or parent not speaking Dutch or French

Trial contacts and locations

1

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Central trial contact

Bieke Samijn, dr.

Data sourced from clinicaltrials.gov

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