Incorporating Avocados in Meals

Loma Linda University (LLU)

Status: Completed

Conditions: Glycemic Index; Satiety; Insulin; Gastrointestinal Peptides and Hormones

Treatments: Dietary Supplement: Avocado included; Dietary Supplement: Avocado supplement

Study type: Interventional

Funder types: Other

Identifiers

NCT01271829

5100220

Details and patient eligibility

About

The purpose of this study is to examine the effect of incorporating avocados in meals on post-ingestion glycemic index, insulin response, sensations of satiety and on appetite-related gastrointestinal peptide and hormone release. Also the effect of consuming avocado containing meals on the caloric intake of participants in subsequent eating episodes will be explored.

Each subject will participate in one intervention for one day, wait one or two weeks, come for another intervention, wait one or two weeks and come for a final intervention- three in total. Participants will be randomly assigned to one of six treatment sequences. Postprandial response to the control and two avocado-containing test meals will be assessed and compared using a 3 x 3 single blind cross-over design. The Subjects will be between 25 and 60 years old, female or male, with a BMI of 23 to 32, stable weight, no sports involvement, non-smoking and not dependent on caffeine. Thirty subjects will be recruited.

Enrollment: 30 patients

Sex: All

Ages: 23 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 23-60 years old
• BMI 23-32
• Stable weight for 6 months
• Live or work near Loma Linda University

Exclusion criteria

• Smoker
• Heavy involvement in sports
• Dependent on caffeine

Trial design

30 participants in 3 patient groups

Control

No Intervention group

Description:

While on the control arm subjects will be given a meal with no avocado.

Avocado supplement

Active Comparator group

Description:

While on the avocado supplement arm subjects will be given a meal in which a given amount of calories will be replaced by calories contributed by avocados.

Treatment:

Dietary Supplement: Avocado supplement

Avocado included

Active Comparator group

Description:

While on the avocado included arm subjects will be given a meal in which the calories of avocado will be added to the calories of the control meal.

Treatment:

Dietary Supplement: Avocado included