Increased CRP Concentrations in Patients Admitted to the Emergency Department With Troponin Elevation Aids to Rule Out Coronary Ischemia

Hillel Yaffe Medical Center

Status: Unknown

Conditions: Myocardial Ischemia

Treatments: Diagnostic Test: Diagnosis of Myocardial Ischemia

Study type: Observational

Funder types: Other

Identifiers

NCT04522583

2020-cardiology-1

Details and patient eligibility

About

The investigators hypothesized that the CRP/troponin ratio measured in patients presenting to the ED with elevated troponin levels could differentiate between patients with cardiac ischemia and those who present due to a systemic inflammatory or infectious disease. The aim of the study was to determine the necessary CRP/troponin ratio required to rule out cardiac ischemia in a large ED population and determine its impact on long-term prognosis.

Enrollment: 15,000 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients admitted to the ED in the period 2016-2019 with cTn level higher than the 99th percentile of cTn concentration in the normal population (>0.014 nanogram/milliliter).

Exclusion criteria

• None

Trial design

15,000 participants in 1 patient group

Troponin-positive ED patients

Description:

All patients admitted to the ED at the Hillel Yaffe Medical Center in Hadera, Israel, in the period 2016-2019 with cTn level higher than the 99th percentile of cTn concentration in the normal population (\>0.014 nanogram/milliliter).

Treatment:

Diagnostic Test: Diagnosis of Myocardial Ischemia