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Increased Extravascular Lung Water in Asymptomatic Open-water Swimmers

D

Dalarna County Council, Sweden

Status

Enrolling

Conditions

Pulmonary Edema - Acute
Extravascular Lung Water

Treatments

Diagnostic Test: Lung auscultation
Diagnostic Test: Body temperature
Diagnostic Test: Peripheral oxygen saturation
Diagnostic Test: Lung ultrasound

Study type

Observational

Funder types

Other

Identifiers

NCT06984120
SIPE - asymptomatic swimmers

Details and patient eligibility

About

Previous studies suggest that increased extravascular lung water might be found in open water swimmers without respiratory symptoms. This study aims to investigate a large number of asymptomatic individuals after an open-water swimming race to assess the prevalence of increased extravascular lung water in asymptomatic open-water swimmers.

Full description

Swimming-induced pulmonary edema (SIPE) can occur during open-water swimming. The pathophysiological mechanisms are still partly unknown, but central pooling of blood volume and peripheral vasoconstriction have been suggested as important factors. SIPE is characterized by acute onset of dyspnea and cough, sometimes with excessive sputum and hemoptysis. The condition usually resolves spontaneously, but medical attention can be required in more severe cases.

Previous studies suggest that SIPE is diagnosed by clinical symptoms, decreased peripheral oxygen saturation and signs of pulmonary edema on lung ultrasound. Interestingly, signs of increased extravascular lung water have been found in divers without respiratory symptoms. There are no similar studies regarding open-water swimmers.

This study aims to investigate a large number of swimmers without respiratory symptoms after finishing an open-water swimming race. Prevalence and amount of increased extravascular lung water after swimming will be assessed by lung ultrasound. In addition, individual baseline factors and information about the race associated with increased extravascular lung water will be evaluated. This study will provide better understanding of the pathophysiological mechanism of SIPE.

Enrollment

570 estimated patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Completion of an open-water swimming race during the "Vansbrosimningen" open-water swimming event
  • No respiratory symptoms (dyspnea and/or cough) during or right after the race
  • Age ≥ 18 years

Exclusion criteria

  • Presence of respiratory symptoms (dyspnea and/or cough) during or right after the swimming race
  • Declines participation

Trial design

570 participants in 1 patient group

Asymptomatic swimmers
Description:
Swimmers (18 years or older) finishing an open-water swimming race during the "Vansbrosimningen" open water swimming event, Sweden, without respiratory symptoms.
Treatment:
Diagnostic Test: Lung ultrasound
Diagnostic Test: Peripheral oxygen saturation
Diagnostic Test: Body temperature
Diagnostic Test: Lung auscultation

Trial contacts and locations

2

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Central trial contact

Maria Hårdstedt, MD, PhD; Claudia Seiler, MD. PhD-student

Data sourced from clinicaltrials.gov

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