Increased Risk of ADHD Among Children With Bilateral Congenital Cataracts

Sun Yat-sen University

Status: Completed

Conditions: Childhood Cataract

Treatments: Other: Psychological and Behavioral Problems

Study type: Observational

Funder types: Other

Identifiers

NCT03692728

CCPMOH2018- China9

Details and patient eligibility

About

In this study, the investigators conducted a cross-sectional, face-to-face investigation to evaluate the behavioral and psychological disorders and the risk of ADHD among children with bilateral congenital cataracts using the Conners'Parent Rating Scale (CPRS) questionnaire, an assessment tool for screening ADHD that obtains parental reports of childhood behavioral problems in research and clinical settings.15-17 Age-matched children with normal vision and the Chinese urban norm were used as controls.

Enrollment: 262 patients

Sex: All

Ages: 3 to 8 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• CC children and NV children aged 3-8 years presenting to the Zhognshan Ophthalmic Center between July and December 2016.

Exclusion criteria

• Patients complicated with systemic manifestations, such as Lowe syndrome, Marfan syndrome, and Down syndrome, were excluded.

Trial design

262 participants in 2 patient groups

CC children

Description:

CC children were registered members of the Childhood Cataract Program of the Chinese Ministry of Health (CCPMOH). All of them were diagnosed with CC by two experienced pediatric ophthalmologists based on a comprehensive evaluation of the onset age (within one year after birth), morphological features of lens opacity, family history, and detailed medical records.

Treatment:

Other: Psychological and Behavioral Problems

NV children

Description:

NV children were recruited from the Optometry Department of the ZOC as the control group. NV was defined as BCVA ≥0.3 (log MAR) in children between 3-5 years old or BCVA ≥0.15 (log MAR) in children older than 5 years. Children with strabismus and high refractive error (myopia or hyperopia: \>6.0 Diopters; astigmatism: \>3.0 Diopters) were excluded from NV group.

Treatment:

Other: Psychological and Behavioral Problems