Increasing COVID-19 Vaccine Uptake in Developing Countries (Bihar)

Yale University

Status: Completed

Conditions: Vaccination Refusal

Treatments: Behavioral: Vaccination made more convenient; Behavioral: Incentives to be vaccinated; Behavioral: Encouragement to wear a mask; Device: Mask; Behavioral: Social mobilization campaign to be vaccinated

Study type: Interventional

Funder types: Other

Identifiers

NCT05225064

2000031541

Details and patient eligibility

About

Working with governments in Bihar, India, we will evaluate a number of mechanisms to increase vaccine uptake. These include household vaccination visits instead of community vaccination clinic.monetary and non-monetary incentives, and concurrent mask promotion. This ClinicalTrials entry contains results only for the study in Bihar.

Full description

The goal of the study is to identify strategies that best promote and support COVID vaccine uptake in developing countries, we propose to test a range of scalable social and behavioural interventions. This could help policy makers design and employ interventions that are effective. This is especially valuable in resource constrained contexts where funds and institutional resources can be diverted towards interventions that have proven to work.

In Bihar the intervention will be village-level social mobilization involving community promotion, including in-person vaccine reinforcement, and household-level social mobilization. Some treatment villages will receive household- level interventions with varying intensity (different proportion of households will be visited). There will also an accompanying mask distribution campaign during household visits where the importance of mask-wearing as a complement to vaccine use will be explained.

This ClinicalTrials entry contains results only for the study in Bihar.

Enrollment: 114,512 patients

Sex: All

Ages: 15+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Lives in study village

Exclusion criteria

• Does not live in study village

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

114,512 participants in 5 patient groups

Control

No Intervention group

Description:

No vaccine or mask promotion, but access to vaccines increased to match access in intervention villages

Village-level vaccine clinics with monetary, non-monetary, or no incentive

Experimental group

Description:

Village-level vaccine clinics with monetary, non-monetary, or no incentive. Villages are cross-randomized to grocery coupon, food ration, no incentive, or grocery coupon to both community member and community health worker after the community member has received a vaccination.

Treatment:

Behavioral: Incentives to be vaccinated

Behavioral: Vaccination made more convenient

Behavioral: Social mobilization campaign to be vaccinated

Household-level vaccination with monetary or no incentive

Experimental group

Description:

Household-level vaccination with monetary incentive or no incentive. Villages are cross-randomized to grocery coupon or no incentive upon receiving vaccination

Treatment:

Behavioral: Incentives to be vaccinated

Behavioral: Vaccination made more convenient

Behavioral: Social mobilization campaign to be vaccinated

Village-level vaccination without incentive, plus mask promotion

Experimental group

Description:

Individuals are encourage to attend village-level vaccine clinics but not given any incentive. Mask distribution and reinforcement activities are conducted in villages at a similar time as vaccine promotion.

Treatment:

Behavioral: Vaccination made more convenient

Device: Mask

Behavioral: Encouragement to wear a mask

Behavioral: Social mobilization campaign to be vaccinated

Village-level vaccination without incentive

Experimental group

Description:

Individuals are encourage to attend village-level vaccine clinics but not given any incentive.

Treatment:

Behavioral: Vaccination made more convenient

Behavioral: Social mobilization campaign to be vaccinated