Increasing HPV Immunization Rates: The Rural Adolescent Vaccine Enterprise (RAVE)

Oregon Health & Science University (OHSU)

Status: Unknown

Conditions: Human Papilloma Virus

Treatments: Behavioral: Practice facilitation

Study type: Interventional

Funder types: Other

Identifiers

NCT03604393

18660

Details and patient eligibility

About

The goal of this study is to engage rural primary care clinics and community organizations to test interventions designed to increase HPV vaccinations in both male and female patients aged 9-26 years.

Full description

The overarching goal of this study is to engage rural primary care clinics and community organizations to test interventions designed to increase HPV vaccinations in both male and female patients aged 9-26 years. Using a step-wedge randomized controlled trial, we will design and test the effectiveness of multi-component primary care practice-based interventions on the completion of the HPV vaccine series and will explore implementation timing in high and low functioning practices to determine how specific characteristics affect the delivery of the full series. Additionally, we will design and test the impact of a community organization-based intervention intended to educate the public about HPV and cancer risk and risk reduction via vaccination.

Enrollment: 22,000 patients

Sex: All

Ages: 18 to 89 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Oregon family medicine and pediatric clinics located in rural communities that see adequate numbers of patients in the age range we are studying (age 11-17 years).

Exclusion criteria

• We will not include neonates, decisionally impaired adults, and prisoners in this study.

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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22,000 participants in 5 patient groups

Practice Facilitation, Cluster 1

Experimental group

Description:

Intervention Cluster 1 is the first intervention arm designed to implement and test the effectiveness of a multi-component primary care practice-based intervention on initiation and completion of the HPV vaccine series as well as reduction in rates of missed opportunities to vaccinate.

Treatment:

Behavioral: Practice facilitation

Practice Facilitation, Cluster 2

Experimental group

Description:

Intervention Cluster 2 is the second intervention arm designed to implement and test the effectiveness of a multi-component primary care practice-based intervention on initiation and completion of the HPV vaccine series as well as reduction in rates of missed opportunities to vaccinate.

Treatment:

Behavioral: Practice facilitation

Practice Facilitation, Cluster 3

Experimental group

Description:

Intervention Cluster 3 is the third intervention arm designed to implement and test the effectiveness of a multi-component primary care practice-based intervention on initiation and completion of the HPV vaccine series as well as reduction in rates of missed opportunities to vaccinate.

Treatment:

Behavioral: Practice facilitation

Practice Facilitation, Cluster 4

Experimental group

Description:

Intervention Cluster 4 is the fourth intervention arm designed to implement and test the effectiveness of a multi-component primary care practice-based intervention on initiation and completion of the HPV vaccine series as well as reduction in rates of missed opportunities to vaccinate.

Treatment:

Behavioral: Practice facilitation

Practice Facilitation, Cluster 5

Experimental group

Description:

Intervention Cluster 5 is the final intervention arm designed to implement and test the effectiveness of a multi-component primary care practice-based intervention on initiation and completion of the HPV vaccine series as well as reduction in rates of missed opportunities to vaccinate.

Treatment:

Behavioral: Practice facilitation