ClinicalTrials.Veeva

Menu

INcreasing Statin Prescribing in HIV Behavioral Economics REsearch (INSPIRE)

University of California, Los Angeles (UCLA) logo

University of California, Los Angeles (UCLA)

Status

Active, not recruiting

Conditions

HIV
Cardiovascular Diseases

Treatments

Behavioral: Provider Feedback
Behavioral: Knowledge assessment
Behavioral: Education Intervention

Study type

Interventional

Funder types

Other

Identifiers

NCT03687060
1U01HL142104-01

Details and patient eligibility

About

Cardiovascular disease is a major cause of morbidity and mortality among people living with HIV. Recent studies have demonstrated that patients with HIV experience a 50-100% increased risk of myocardial infarction and stroke compared to HIV-uninfected persons. They also face higher risks of stroke, sudden death, and heart failure. However, evidence-based statin therapy-which is safe in this population and highly effective at reducing cardiovascular risk-is under-prescribed. The investigators propose a multi-level intervention to increase evidence-based statin prescribing by addressing barriers at these levels. The implementation intervention includes two strategies: (1) tailored education at the leadership, provider, and patient levels, and (2) behavioral economics-informed feedback for providers.

Enrollment

75 patients

Sex

All

Ages

40+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • age ≥ 40 years
  • have been diagnosed with HIV
  • LDL ≥ 190, diabetes and LDL ≥ 70
  • or 10-year ASCVD risk ≥ 7.5%
  • or history of heart attack, stroke, or peripheral vascular disease
  • care for patients with HIV at least 1/2 day each week (physicians)
  • work at participating clinics (physicians)

Exclusion criteria

  • unable to provide written, informed consent
  • not at participating clinic

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

75 participants in 3 patient groups

Organization Level
Other group
Treatment:
Behavioral: Knowledge assessment
Provider Level
Other group
Treatment:
Behavioral: Provider Feedback
Behavioral: Knowledge assessment
Behavioral: Education Intervention
Patient Level
Other group
Treatment:
Behavioral: Knowledge assessment

Trial contacts and locations

8

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems