Increasing Uptake of Colorectal Cancer Screening in Ontario

Sunnybrook Health Sciences Centre

Status: Completed

Conditions: Colorectal Disorders

Treatments: Other: Mailed invitation; Other: FOBT kit

Study type: Interventional

Funder types: Other

Identifiers

NCT01629004

308-2010

Details and patient eligibility

About

The investigators hope to determine whether the addition of an FOBT kit and educational materials to a second mailed invitation compared to a second mailed invitation alone increases use of appropriate screening tests (FOBT for average risk or colonoscopy if increased risk) by eligible persons within 6 months of the second mailing in: (1)Non-responders to an initial mailed CRC screening invitation from their family physician and, (2)Those who responded to the initial mailed CRC screening invitation and are due for repeat screening (i.e., "recall" patients). In addition, the investigators will also explore the impact of the investigators intervention in likely under-screened groups such as those living in more remote areas of the province and those with low socio-economic status as well as assessing the cost-effectiveness of this strategy.

Enrollment: 5,155 patients

Sex: All

Ages: 50 to 74 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Recipients of a mailed CRC screening invitation through the CCO Invitation Pilot project
• No OHIP record of completion of FOBT since initial mailing (Non-responders arm only)
• No OHIP of 'CRC Cancer Screening Exclusion' tracking code since initial mailing (Non-responders arm only)
• An OHIP record of completion of FOBT 6 months since initial mailing (Recall arm only)
• Negative result according to LRT or if not in LRT, no record of interval colonoscopy in CIRT or OHIP (Recall arm only)

Exclusion criteria

• Age greater than 74 years at time of mailing
• Interval diagnosis of colorectal cancer
• Interval colonoscopy or flexible sigmoidoscopy
• Interval departure from Pilot physician's practice
• Death
• Presently institutionalized
• Physician has declined participation in the study
• Interval record of repeat FOBT (Recall arm only)

Trial design

Primary purpose: Screening

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Single Blind

---

5,155 participants in 2 patient groups

Non-responders

Other group

Description:

Non-responders to an initial mailed CRC screening invitation from their family physician. FOBT kit. Mailed invitation.

Treatment:

Other: FOBT kit

Other: Mailed invitation

Recall patients

Other group

Description:

Those who responded to the initial mailed CRC screening invitation and are now due for repeat screening (i.e., "recall" patients). FOBT kit. Mailed invitation.

Treatment:

Other: FOBT kit

Other: Mailed invitation