Incubation of Alcohol Craving During Abstinence

National Institute on Drug Dependence, China

Status: Completed

Conditions: Alcohol Dependence

Study type: Observational

Funder types: Other

Identifiers

NCT01991704

nidd_peking

Details and patient eligibility

About

In order to determine whether the 'incubation of craving' phenomenon also occurred in alcoholics, investigators employed an experimental approach to investigate the time course of cue-induced craving in alcoholism. Eighty male participants were randomly divided into Four groups, and they were assessed at 7, 14, 30, and 60 days of abstinence for cue-induced alcohol craving . Another group including 19 patients was repeatedly tested for the cue-induced alcohol craving at the above abstinence days. Other psychological and physiological measures were administered at the four abstinence time points.

Full description

All subjects provided written informed consent after a full explanation of the protocol design.

Enrollment: 99 patients

Sex: Male

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• met the criteria of DSM-IV for alcohol dependence
• aged 18-60 years,male

Exclusion criteria

• current or past history of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) axis I disorders
• with other serious physical diseases (respiratory disorders, cardiovascular disease and so on)
• other drug abuse except for nicotine