Indicators of Inflammation and Coagulation in Sepsis

University of Oklahoma (OU)

Status: Completed

Conditions: Sepsis

Study type: Observational

Funder types: Other

Identifiers

NCT01128283

09681

Details and patient eligibility

About

We will collect blood samples from patients with the diagnosis of sepsis and other ICU patients. We will describe the course of different mediator levels and organ injury markers and follow their progression throughout the course of the study.

Full description

After informed consent is obtained 5 cc of blood is collected on the day of admission and on days 0, 1, 3, and 7 thereafter. Plasma is collected and frozen for the subsequent measurement of biomarkers.

Enrollment: 500 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Admission to the ICU

Exclusion criteria

• No blood draws scheduled
• Hemoglobin level < 6,5 gm/dl

Trial design

500 participants in 2 patient groups

Sepsis

Description:

Patients with severe sepsis

Non-infected

Description:

ICU patients without evidence of infection