Individual Approach for Bowel Preparation Before Colonoscopy

Maria Sklodowska-Curie National Research Institute of Oncology

Status: Completed

Conditions: Split-dose Bowel Preparation; Polyethylene Glycol Solution; Risk Factors Inadequate Preparation

Treatments: Other: individual preparation for colonoscopy

Study type: Interventional

Funder types: Other

Identifiers

NCT01476735

Individual bowel preparation

Details and patient eligibility

About

This is a prospective, randomized, single-blind study designed to evaluate the influence of individual approach on bowel preparation quality for colonoscopy. The investigators compare split-dose polyethylene glycol solution (PEG, Fortrans, Beaufour Ipsen) to modified split-dose PEG regarding predictors of inadequate preparation for colonoscopy.

Full description

Up to 22% of patients are not good prepared for colonoscopy and it is caused of aborted procedures and increased costs. There are identified predictors of inadequate bowel preparation before colonoscopy, but we still don't know if an individual approach improve the quality of preparation.

Enrollment: 266 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• men and women more than 18 years of age undergoing colonoscopy for routine clinical indications
• provided written informed consent

Exclusion criteria

• lack of written informed consent or inability to provide informed consent or refusal to consent to the study
• pregnancy and breast feeding
• known allergy to PEG or bisakodyl
• presence of serious conditions such as severe cadiac, renal or metabolic diseases, major psychiatric illness or end-stage cancer disease requiring taking narcotic drugs
• colonoscopy performed under conscious sedation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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266 participants in 2 patient groups

split-dose polyethylene glycol solution

Active Comparator group

Description:

first dose (1,5 l) of polyethylene glycol solution taken at 6-7.00 in the evening before colonoscopy, second dose (1,5 l) taken at 5.30-6.00 in the morning of a day of colonoscopy; additional bisacodyl taken at 12.00 at the day before colonoscopy

Treatment:

Other: individual preparation for colonoscopy

Individual preparation for colonoscopy

Active Comparator group

Treatment:

Other: individual preparation for colonoscopy