Individual Patient Compassionate Use of Nirogacestat

SpringWorks Therapeutics

Status

Conditions: Desmoid Tumor; NOTCH Gene Mutation Positive Tumors

Treatments: Drug: Nirogacestat (Gamma Secretase Inhibitor)

Study type: Expanded Access

Funder types: Industry

Identifiers

NCT05041036

NIR-DT-701

Details and patient eligibility

About

This program is being offered on a patient by patient basis and will require company, Institutional Review Board/Independent Ethics Committee, and applicable competent authority approval.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Patient has a serious, debilitating or life-threatening medical condition that cannot be treated satisfactorily with an authorized medicinal product or other available standard treatment options, or all other treatment options have been exhausted.
• Patient does not qualify to participate in an ongoing clinical trial.