Individual Response to Different Volumes of Resistance Training

Inland Norway University of Applied Sciences

Status: Completed

Conditions: Healthy

Treatments: Behavioral: 12-week progressive strength training protocol

Study type: Interventional

Funder types: Other

Identifiers

NCT02179307

Trainsome 2014#002

Details and patient eligibility

About

The literature is not clear as to which training volume to employ during initial phases of resistance training programs to ensure optimal muscular adaptations. The purpose of this study is therefore to compare effects of strength training with low versus moderate volume on muscular function and hypertrophy in previously untrained, healthy individuals. Furthermore, the investigators will relate individual variation in responses to proxy markers of individual training state, such as baseline muscular function and muscle fiber type.

The study will include 25 women and 25 men and will consist of a 12-week resistance training protocol. Each study participant will act as their own control, performing both the low- (1-set) and the moderate-volume (3-sets) protocol, allocated to either the dominant or non-dominant leg, in a stratified and randomized fashion.

Primary outcome measures are thigh muscle cross section area and unilateral knee extension strength. Additionally, muscle fiber type composition will be evaluated as well as additional parameters of muscular function.

The primary hypothesis is that low-volume protocols will be beneficial for individuals with glycolytic muscle phenotypes, whereas the opposite will be true for individuals with more aerobic phenotypes.

Enrollment: 42 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy
• Non-smoking
• Able to tolerate resistance exercise training

Exclusion criteria

• Presence or history of cardiovascular, metabolic, endocrine or neuromuscular disease
• Diagnosed mental health disorder
• Intolerance to local anesthetic
• No experience with exercise training
• Performing regular resistance training (more than 1 session per week during last 12 months)
• Impaired strength/ neuromuscular function due to previous injury
• Recurrent pain in lower back, knee or shoulders
• Taking prescribed medication that may affect outcome of training intervention

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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42 participants in 1 patient group

Arm label 1-Set, 3-Set

Experimental group

Description:

12-week progressive strength training protocol of different volumes

Treatment:

Behavioral: 12-week progressive strength training protocol