Individualized Brain Stimulation Using Transcranial Direct Current Stimulation Simulation in Stroke Patients

Samsung Medical Center

Status: Completed

Conditions: Stroke

Treatments: Device: Transcranial Direct Current Stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT04699331

2019-07-107

Details and patient eligibility

About

This study is to investigate the effect of transcranial direct current stimulation (tDCS) simulation-based individualized stimulation compared to conventional stimulation and sham stimulation.

Enrollment: 24 patients

Sex: All

Ages: 19 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Unilateral stroke patients
• Chronic patients over 6 months after onset
• Patients with motor evoked potential of the first dorsal interosseous muscle
• Patients with the movement of fingers

Exclusion criteria

• History of psychiatric disease
• Significant other neurological diseases except for stroke
• Difficult to perform this experiment
• Patients who are deemed difficult to participate in this research by the investigator
• Patients with metal implants and medical devices
• History of epilepsy
• Pregnancy
• Skin defect at the site of electrode attachment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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24 participants in 3 patient groups

Individualized stimulation group

Experimental group

Description:

Patients receive five sessions of individualized stimulation obtained from brain image-based transcranial direct stimulation simulation. The simulator generates the electrode's location on the scalp.

Treatment:

Device: Transcranial Direct Current Stimulation

Conventional stimulation group

Active Comparator group

Description:

Patients receive five sessions of conventional stimulation with electrodes over C3 and C4 based on the 10-20 system.

Treatment:

Device: Transcranial Direct Current Stimulation

Sham stimulation group

Sham Comparator group

Description:

Patients receive five sessions of sham stimulation with electrodes over C3 and C4 based on the 10-20 system.

Treatment:

Device: Transcranial Direct Current Stimulation