Individualized Lung Recruitment Maneuver Guide by Pulse-oximetry in Anesthetized Patients

Fundación para la Investigación del Hospital Clínico de Valencia

Status: Completed

Conditions: Abdominal Cancer

Treatments: Other: Open-lung approach

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT02912819

SpO2-guide RM

Details and patient eligibility

About

General anesthesia and mechanical ventilation promotes atelectasis and airway closure. The open-lung approach (OLA) strategy restores the functional residual capacity. Pulse oximetry hemoglobin saturation (SpO2) using room air can diagnose shunt induced by lung collapse during general anesthesia and the SpO2 breathing air was useful to detect the lung´s opening and closing pressure during a recruitment maneuver (RM) in morbidly obese anesthetized patients.

Investigators hypothesized that the SpO2 breathing air can personalize the open-lung approach.

Full description

Increase in airway pressure until the SpO2 reaches 97% (lung´s opening pressure) during the incremental positive end-expiratory (PEEP) limb. Decrease in the PEEP level until the SpO2 decreases bellow 97% (lung´s closing pressure)

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Non-obese patients with ASA physical status I-III undergoing elective abdominal laparoscopic surgery with an expected operating time of less than 2 hours were included.

Exclusion criteria

• age of <18 years,
• preoperative SpO2 ≤97% while breathing room air, and
• patients with previous known cardiac or respiratory disease.