Individualized Molecular Profiling for Allocation to Clinical Trials (IMPACT) Project

National Cancer Centre, Singapore

Status: Enrolling

Conditions: Solid Tumor

Study type: Observational

Funder types: Other

Identifiers

NCT02806388

ECRU-IMPACT

Details and patient eligibility

About

This study aims to screen tumor molecular profile for better selection of anticancer treatment, in particular, allocation to clinical trials if available.

Full description

Molecular profiling will be performed on archival tumor tissue or freshly collected tumor tissue from re-biopsy. Blood, pleural fluid, FNA, and/or saliva may be collected to study the genetic makeup and also to compare the tumor molecular profile. Personalized therapy will be given based on molecular profile.

Enrollment: 5,500 estimated patients

Sex: All

Ages: 12+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Confirmed histological diagnosis of solid tumor
• Suitable for systematic treatment and clinical trials
• ECOG (Eastern cooperative oncology group) performance status < 2
• Able to provide tumor tissue for molecular profiling
• Able to understand and sign the informed consent form

Exclusion criteria

• None

Trial design

5,500 participants in 1 patient group

tumor tissue for molecular profiling