Individualized Positive End-expiratory Pressure Evaluation Using the Intratidal Compliance-volume Profile in Children

Seoul National University

Status: Completed

Conditions: Lung Compliance

Treatments: Procedure: Positive end expiratory pressure (PEEP)

Study type: Interventional

Funder types: Other

Identifiers

NCT03533296

H1804-101-938

Details and patient eligibility

About

The investigators assess the changes in respiratory compliance according to different levels of positive end expiratory pressure (PEEP) in children under general anesthesia. In addition, the investigators evaluate the intratidal compliance-volume profile at each PEEP level and determine the optimal PEEP level during anesthesia.

Enrollment: 47 patients

Sex: All

Ages: Under 6 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children undergoing surgery more than 1 hour under general anesthesia
• American Society Anesthesiologist physical status I, II

Exclusion criteria

• History of lung resection
• History of bronchopulmonary dysplasia or respiratory distress syndrome
• Abnormalities in chest radiography
• Laparoscopic surgery
• Abdominal surgery

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

47 participants in 1 patient group

Children

Experimental group

Description:

Children who receive elective surgery under general anesthesia and are supported by mechanical ventilation

Treatment:

Procedure: Positive end expiratory pressure (PEEP)