Individualized Strategies of Red Blood Cell Transfusion for Perioperative Pediatric Patients

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Fudan University

Status

Withdrawn

Conditions

Individualized Transfusion Strategy
Clinical Outcome
Perioperative Pediatric Patient
Red Blood Cell

Treatments

Diagnostic Test: clinical condition score

Study type

Interventional

Funder types

Other

Identifiers

NCT04537000
transfusion-08-2020

Details and patient eligibility

About

The individualized strategies of red blood cell for perioperative pediatric patients are made based on the comparison between the clinical condition score and the Hb concentration.

Full description

The hypothesis is that the individual transfusion strategies will help to save blood resource, and meanwhile will not adversely affect the patients' clinical outcomes. Participants will be randomly divided into two groups, where the strategies of transfusion of red blood cell will be made following different principles. The strategies for patients in control group will be made by the attending doctors in charge according to the current Chinese red blood cell transfusion guidelines. For the patients in study group, the clinical condition will be identified every time red blood cell transfusion is considered. The strategies will be made according to the comparison between the score and the Hb concentration. The volume of the red blood cell used in these two groups will be compared. The number of patients who need transfusion in these two groups will be compared. The clinical outcomes will also be compared between the two groups.

Sex

All

Ages

1 month to 18 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

The Hb concentration is tested before operation. It is higher than 7g/dl and lower than 10g/dl. Or it is anticipated that it will decrease lower than 10g/dl.

Exclusion criteria

  • The patient will not undergo an operation.
  • newborn or premature baby
  • patients accompanied with hemorrhagic disease or cyanotic heart disease
  • patients with ischemic heart disease or ischemic cerebrovascular disease

Trial design

Primary purpose

Health Services Research

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

0 participants in 2 patient groups

control group
No Intervention group
Description:
The strategies of red blood cell transfusion for the pediatric patients in this group will be made by the attending doctors in charge based on the current transfusion guidelines. The attending doctors decide when to start blood red cell transfusion and order the volume of the blood red cell as the usual clinical practice.
study group
Experimental group
Description:
For study group, the clinical condition score must be identified every time red blood cell transfusion is considered. The strategies of red blood cell transfusion for the pediatric patients in this group, including the trigger and the volume, will be made based on the comparison between the clinical condition score and the Hb concentration.
Treatment:
Diagnostic Test: clinical condition score

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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