Indocyangreen Elimination in Cirrhosis and Acute Liver Failure

Heidelberg University

Status: Completed

Conditions: Acute Liver Failure; Liver Cirrhosis

Treatments: Procedure: Indocyangreen (ICG) clearance

Study type: Observational

Funder types: Other

Identifiers

NCT00245310

LiMON

Details and patient eligibility

About

Indocyangreen (ICG)is totally biliary eliminated and corresponds to hepatocyte function and liver perfusion.

The ICG-clearance will be evaluated as a prognostic marker in liver disease.

Full description

patients with acute liver failure or advanced liver disease will be studied. ICG-clearance will be correlated with established clinical scores and outcome.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• acute liver failure OR end-stage liver disease
• normal hepatic perfusion by doppler ultrasound

Exclusion criteria

• portal vein thrombosis
• allergy to ICG or iodine
• thyroid disease