Indocyanine Green Lymphography in Management of Lingual Lymphatic Malformation

Nanjing Children's Hospital

Status: Completed

Conditions: Lymphatic Malformation

Treatments: Procedure: ICGL-guided treatment; Procedure: Conventional Treatment group

Study type: Interventional

Funder types: Other

Identifiers

NCT06755905

NanjingCH0116651

Details and patient eligibility

About

To elucidate the application of indocyanine green (ICG) fluorescence angiography in the treatment of childhood tongue cLM (clinically localized malignancy, presumed context here), providing a clearer scientific basis for subsequent targeted interventions.

Enrollment: 42 patients

Sex: All

Ages: Under 14 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• No previous intervention
• more than 6 months post-treatment follow-up
• Stage I or Stage IIa

Exclusion criteria

• History of iodine allergy
• Syndromic cLM
• Severe liver and kidney dysfunction

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

42 participants in 2 patient groups

lingual LM with ICGL-guided treatment

Experimental group

Description:

indocyanine green lymphography guided resection combined with sclerotherapy

Treatment:

Procedure: ICGL-guided treatment

Conventional treatment

Active Comparator group

Description:

lingual LM with conventional treatment

Treatment:

Procedure: Conventional Treatment group