Indole-3-Carbinol Effects on Estrogen Metabolism

University of Wisconsin (UW)

Status and phase: Terminated; Phase 2

Conditions: Obesity

Treatments: Dietary Supplement: Indole-3-carbinol

Study type: Interventional

Funder types: Other

Identifiers

NCT00988845

A532800 (Other Identifier)

CC09709 (Other Identifier)

H-2009-0093

SMPH\OBSTET & GYNECOL\OB-GYN (Other Identifier)

Details and patient eligibility

About

This study will test a dietary supplement, indole-3-carbinol, for improving the estrogen profile in women across a range of body mass index.

Enrollment: 38 patients

Sex: Female

Ages: 30 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• woman aged from 30 - 50 years
• regular menstrual cycle

Exclusion criteria

• taking hormone replacement or hormonal contraception
• thyroid disorder
• uncontrolled asthma
• BMI under 18.5
• allergy to cruciferous vegetables

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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38 participants in 1 patient group

Indole-3-carbinol

Experimental group

Treatment:

Dietary Supplement: Indole-3-carbinol