Induced Motion Illusions Through Vision and Tendon Vibrations: Study of Interactions in Hemiplegic Subjects (OPTIVIBE)

Centre Hospitalier Universitaire de Saint Etienne

Status: Terminated

Conditions: Hemiplegia

Treatments: Device: Computerized Mirror Therapy (CMT); Device: Tendon vibration

Study type: Interventional

Funder types: Other

Identifiers

NCT04449328

19CH113

2019-A01673-54 (Other Identifier)

Details and patient eligibility

About

Two movement illusion techniques can currently be used in clinical practice for motor rehabilitation after stroke hemiplegia: visual illusion (mirror therapy) and proprioceptive illusion (tendon vibration). Mirror therapy, in its computerized version (IVS3, Dessintey, Saint-Etienne, France), is based on the substitution of the deficient visual feedback by a visual feedback of a correctly realized movement. The proprioceptive illusion is based on the external application of a vibrator on muscle tendons at a frequency between 50 and 120 Hz. These two techniques are currently used independently. They are, in theory, complementary and additive. No study has described the combinatorial properties of the illusions generated by these 2 techniques in hemiplegic subjects and healthy subjects.

Full description

The study hypothesis is that the administration of mirror therapy together with vibration will increase the perception of movement in a subjective scale.

Enrollment: 33 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Hemiplegic subjects :

• Male or female
• Aged 18 to 70 years,
• First ischemic or hemorrhagic stroke causing hemiplegic
• Having signed the written consent
• Affiliated or entitled to a social security scheme

Healthy subjects :

• Male or female, aged 18 to 70 years,
• Matched in sex, age and laterally with hemiplegic subjects
• Having signed the written consent
• Affiliated or entitled to a social security scheme

Exclusion criteria

Hemiplegic subjects :

• With complete lesion of the primary motor cortex
• With an addiction to alcohol or drugs
• With psychiatric illness, cognitive impairment, uncontrolled disease/epilepsy, malignant illness severe kidney or lung disease
• With history of associated general disabling disease
• With cerebellar syndrome
• With clinical brain stem involvement
• Under legal protection
• Pregnant or breastfeeding women

Healthy subjects :

• Neurological, cardiovascular, musculoskeletal diseases
• Taking medication that can affect attention
• Unable to understand instructions of the study
• Under legal protection
• Pregnant or breastfeeding women

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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33 participants in 2 patient groups

Patient with first stroke causing hemiplegic

Experimental group

Description:

Patient with first stroke causing hemiplegic will be included. They will have Computerized Mirror Therapy (CMT) associated at tendon vibration: * Visit 1: wrist flexion (right and left arms) with 5 randomized experimental conditions (vision+vibration, vision alone, vibration alone, static image+vibration, vision of extension+vibration(incongruence)) * Visit 2 (1 week later): wrist extension (right and left arms) with 5 randomized experimental conditions (vision+vibration, vision alone, vibration alone, static image+vibration, vision of flexion+vibration (incongruence)) These conditions will be recording by the Kinovea software, which allows the measurement of angles and amplitudes.

Treatment:

Device: Tendon vibration

Device: Computerized Mirror Therapy (CMT)

healthy subjects

Sham Comparator group

Description:

Healthy subjects will be included. They will have Computerized Mirror Therapy (CMT) associated at tendon vibration: * Visit 1: wrist flexion (right and left arms) with 5 randomized experimental conditions (vision+vibration, vision alone, vibration alone, static image+vibration, vision of extension+vibration(incongruence)) * Visit 2 (1 week later): wrist extension (right and left arms) with 5 randomized experimental conditions (vision+vibration, vision alone, vibration alone, static image+vibration, vision of flexion+vibration (incongruence)) These conditions will be recording by the Kinovea software, which allows the measurement of angles and amplitudes.

Treatment:

Device: Tendon vibration

Device: Computerized Mirror Therapy (CMT)