Induction and Recognition of Emotions (IRE)

University of Valencia

Status: Withdrawn

Conditions: Alzheimer's Disease; Parkinson's Disease; Healthy Older Adults

Treatments: Diagnostic Test: Memory alteration test (M@T); Diagnostic Test: Rey-Osterrieth Complex Figure Test (ROCFT); Diagnostic Test: Global Deterioration Scale (GDS); Diagnostic Test: Barcelona test (BT); Diagnostic Test: Frontal assessment battery (FAB); Diagnostic Test: Beck Depression Inventory-II (BDI-II); Diagnostic Test: Positive and Negative Affect Scale (PANAS); Diagnostic Test: Spanish-Complutense Verbal Learning Test (TAVEC); Diagnostic Test: Auto-Assessment Manikins (SAM); Diagnostic Test: Mini Cognitive Examination (MCE)

Study type: Observational

Funder types: Other

Identifiers

NCT04353947

UV-INV_ETICA-1217558

Details and patient eligibility

About

This study evaluates the differences in cognitive function between healthy older adults, older adults with mild Alzheimer's type dementia and older adults with Parkinson's disease and if there are differences in valence assessment and activation that produce them a mood induction task. Subjects are assessed using neuropsychological tests and then a mood induction task based on movie clips is applied.

Full description

Different neuropsychological tests will be used to assess the differences in cognitive function in the different groups, whose scores are expected to be lower in the group of older adults with Alzheimer's disease (AD) and older adults with Parkinson's disease (PD).

After studying the cognitive function in the different groups, we proceed to check through a task based on movie clips if there are also differences in the valence assessment (liking/disliking depending on the emotion induced by scenes from different films) and activation (excitement caused by each one of the movie scenes), hoping to find differences for the negative emotions taking into account the cognitive difficulties that both (the EA group and the EP group) may have for processing this type of cognitively more demanding information; instead, it is possible that the positivity effect continues to affect these patients so that for positive emotions there are no differences between the different groups.

Sex: All

Ages: 65 to 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

For the group of healthy older adults:

• MEC score greater than 26 points.
• GDS between 1 and 3.

For the mild EA group:

• MEC score between 18 and 23 points.
• GDS between 3 and 4.

For the EP group:

• MEC score greater than 23 points.
• GDS between 1 and 3.
• FAB score equal to or less than 11 points.

General Exclusion Criteria:

Participants cannot have:

• Significant asymptomatic neurovascular disease
• History of previous symptomatic stroke
• Alcohol or drug abuse/dependence
• Severe psychiatric symptoms
• Depressive symptoms higher than mild

Trial design

0 participants in 3 patient groups

Healthy older adults

Description:

Healthy older adults with 65 years or older

Treatment:

Diagnostic Test: Rey-Osterrieth Complex Figure Test (ROCFT)

Diagnostic Test: Positive and Negative Affect Scale (PANAS)

Diagnostic Test: Global Deterioration Scale (GDS)

Diagnostic Test: Barcelona test (BT)

Diagnostic Test: Memory alteration test (M@T)

Diagnostic Test: Beck Depression Inventory-II (BDI-II)

Diagnostic Test: Spanish-Complutense Verbal Learning Test (TAVEC)

Diagnostic Test: Auto-Assessment Manikins (SAM)

Diagnostic Test: Mini Cognitive Examination (MCE)

Older adults with Alzheimer's disease

Description:

Older adults with Alzheimer's disease with 65 years or older

Treatment:

Diagnostic Test: Rey-Osterrieth Complex Figure Test (ROCFT)

Diagnostic Test: Positive and Negative Affect Scale (PANAS)

Diagnostic Test: Global Deterioration Scale (GDS)

Diagnostic Test: Barcelona test (BT)

Diagnostic Test: Memory alteration test (M@T)

Diagnostic Test: Beck Depression Inventory-II (BDI-II)

Diagnostic Test: Spanish-Complutense Verbal Learning Test (TAVEC)

Diagnostic Test: Auto-Assessment Manikins (SAM)

Diagnostic Test: Mini Cognitive Examination (MCE)

Older adults with Parkinson's disease

Description:

Older adults with Alzheimer's disease with 65 years or older

Treatment:

Diagnostic Test: Rey-Osterrieth Complex Figure Test (ROCFT)

Diagnostic Test: Positive and Negative Affect Scale (PANAS)

Diagnostic Test: Global Deterioration Scale (GDS)

Diagnostic Test: Barcelona test (BT)

Diagnostic Test: Memory alteration test (M@T)

Diagnostic Test: Beck Depression Inventory-II (BDI-II)

Diagnostic Test: Spanish-Complutense Verbal Learning Test (TAVEC)

Diagnostic Test: Auto-Assessment Manikins (SAM)

Diagnostic Test: Frontal assessment battery (FAB)

Diagnostic Test: Mini Cognitive Examination (MCE)