Inert Gas Rebreathing in Ventilated Patients (VIGR)

Universitätsmedizin Mannheim

Status: Unknown

Conditions: Renal Failure; Respiratory Failure; Heart Failure; Sepsis

Treatments: Device: non-invasive determination of cardiac output

Study type: Observational

Funder types: Other

Identifiers

NCT01891253

VIGR_MA

Details and patient eligibility

About

Measuring hemodynamic parameters in ventilated patients is important yet still complicated to perform. Inert gas rebreathing (IGR) showed promising results when being compared to other invasive as well as non-invasive techniques for the measurement of cardiac output. The aim of our study is to evaluate the feasibility of IGR in ventilated patients.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age 18 - 80 years
• mechanically ventilated patient
• existing PiCCO arterial line

Exclusion criteria

• FiO2 > 60% (fraction of inspired oxygen)
• PEEP > 10 mmHg (positive end-expiratory pressure)
• SO2 < 90% (oxygen saturation )
• Systolic blood pressure < 90 mmHg
• Heart rate > 150 bpm
• APRV (airway pressure release ventilation)
• ICD (implantable cardioverter defibrillator) / pace maker
• [ Anaesthetic Conserving Device (Anaconda) ]

Trial design

50 participants in 1 patient group

ventilated patients

Description:

ventilated patients in an internal medicine ICU with existing PiCCO invasive hemodynamic monitoring

Treatment:

Device: non-invasive determination of cardiac output