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Infant Feeding Practices in Transition: Breast Milk Intake, Complementary Feeding and Body Composition During Infancy

M

Mahidol University

Status

Completed

Conditions

Breast Feeding

Treatments

Other: no intervention

Study type

Observational

Funder types

Other

Identifiers

NCT04020640
MU-IRB 2012/114.0712

Details and patient eligibility

About

Research Aim: We assessed human milk intakes of Thai infants during the first 6 months comparing exclusive (EBF), predominant (PBF) and partial (PartBF) breastfeeding.

Methods: One-hundred and ten apparently healthy Thai lactating mother-infant pairs were followed from birth. Human milk intakes were determined at 6 weeks, 3 and 6 months, using the DTM method. Daily energy and protein intakes were assessed using 3-day non-consecutive 24-hour recalls. Socio-demographic characteristics were collected using a questionnaire. For comparisons among breastfeeding practices, one-way ANOVA with Tukey's post hoc test was used for normally distributed data, or Kruskal-Wallis Test with Mann-Whitney U Test for not normally distributed data.

Full description

Human milk intakes were comparable between the EBF and PBF infants during the first 6 months, and provided the sole source of energy and protein; infant formula largely replaced breast milk among PartBF infants.

Enrollment

110 patients

Sex

All

Ages

2 weeks to 6 months old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Apparently healthy women aged 20-35 year
  • Had pre-pregnancy BMI in the normal range (18.5-25 kg/m2)
  • Planned to breastfeed their baby for at least 6 months
  • Being full term infants (gestational age 37-42 weeks) and singleton
  • Had normal birth weight (2,500 - 4,000 g)
  • Signed written informed consent to participate in the study

Exclusion criteria

  • Infant: preterm; twin; low and high birth weight; congenital diseases
  • Mother: chronic diseases needed to get medicine and treatment; underweight and obesity
  • Mother and baby did not stay together throughout 12 months of infant age

Trial design

110 participants in 3 patient groups

Exclusive breastfeeding (EBF)
Description:
provision of breast milk only, allowing only receiving oral rehydration salts (ORS), drops and syrups (vitamins, minerals, medicines) as necessary
Treatment:
Other: no intervention
Predominant breastfeeding (PBF)
Description:
providing breast milk plus other liquids (water and water-based drinks, fruit juice) and ORS, drops and syrups (vitamins, minerals, medicines)
Treatment:
Other: no intervention
Partial breastfeeding (PartBF)
Description:
provision of breast milk plus infant formula or cow milk or other solid/semi-solid complementary foods
Treatment:
Other: no intervention

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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