Infantile - Postoperative Residual Curarization - Study (I-PORC)

University of Regensburg (UR)

Status: Completed

Conditions: Neuromuscular Monitoring; Postoperative Residual Curarization; Neuromuscular Blockade

Treatments: Diagnostic Test: Acceleromyography

Study type: Observational

Funder types: Other

Identifiers

NCT03804346

17-449-101

Details and patient eligibility

About

The primary object of this study is, to investigate the current procedure of neuromuscular monitoring at a tertiary academic university medical center.

Full description

Residual neuromuscular block is known to be a significant but frequently overlooked complication after the use of neuromuscular blocking agents. Aim of this prospective, observational study is to detect the incidence and severity of residual paralysis at a tertiary academic german university medical center.

Methods:

All infantile patients recieving neuromuscular blocking agents are included over a 12 week observational period. At the end of the operation procedure, directly prior to tracheal extubation a train-of-four ratio was assessed quantitatively by an independet observer using the TOF Watch SX monitor. Data related to patient postoperative outcome were collected in the operating theatre, during the way to the postoperative care unit (PACU) and during the stay in the PACU:

• incidence of residual paralysis
• incidence of aspiration, bronchospasm, laryngospasm, oxygen desaturation, airway obstruction,

Enrollment: 100 patients

Sex: All

Ages: 1 month to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• General aneasthesia with muscle relaxation
• Children between 1 Month to 18 Years
• Endotracheal Intubation due to surgical or diagnostical procedures

Exclusion criteria

• older than 18 years
• local aneasthesia
• regional aneasthesia
• larynx mask
• patient comes from ICU
• children who are not planned to be extubated