Infants Colics : Towards a Migrainous Origin ? (COLIGRAINE)

Central Hospital, Nancy, France

Status: Unknown

Conditions: Migraine Equivalents; Colic, Infantile; Migraine

Treatments: Other: Non interventional study

Study type: Observational

Funder types: Other

Identifiers

NCT03155360

2017-A00185-48

Details and patient eligibility

About

According to recent studies, we want to find evidences that infant colics could be a episodic symptom associated to migraine as cyclic vomiting syndrome or abdominal migraine are. The main purpose is to compare the presence of colics in infants between 60 days and 180 days of life and the presence of migraine in their parents to determine if colicky children's parents are more migrainous than other parents.

Full description

Recent studies shows that :

• Infants with colics have more probability to become migrainous when they will grow up
• Migrainous children have more colic history in their past
• Migrainous parents have more babies with colics than non-migrainous parents

According to these studies, we want to find othen evidences that infant colics could be a migraine equivalent as cyclic vomiting syndrome or abdominal migraine are. Recently, the international classification of headache disease IIIbeta added in its appendix colics in the episodic symptoms associated to migraine

The main purpose of our study in the pediatric emergency unit of Nancy is to compare the presence of colics in infants and the presence of migraine in their parents to determine if colicky children's parents are more migrainous than other parents. The data collection will be made thanks to a survey which will be completed by the parents.

Enrollment: 300 estimated patients

Sex: All

Ages: 60 to 180 days old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All infants between 60 days and 180 days of life who comes to the Nancy University Hospital pediatric emergency unit

Exclusion criteria

• Language barrier of parents

Trial design

300 participants in 2 patient groups

Infant with colics

Description:

Infants with colics according to Wessel definition : * Recurrent episodes of irritability, fussing or crying from birth to 4 months of age * Episodes last for 3 hours per day ; on 3 days per week ; for 3 weeks * Episodes can not be attributed to another disorder

Treatment:

Other: Non interventional study

Infant without colics

Treatment:

Other: Non interventional study