Infections With Enterobacteria Producing Carbapenemases at the University Hospitals of Strasbourg (CARBA)

University Hospital, Strasbourg, France

Status: Unknown

Conditions: Nfections, Enterobacterial

Study type: Observational

Funder types: Other

Identifiers

NCT04995965

8297 (Other Identifier)

Details and patient eligibility

About

Infections with enterobacteria producing carbapenemases at the University Hospitals of Strasbourg - descriptive epidemiology and risk factors for infection in the event of colonization

There is a worrying situation of an increase in the number of patients colonized with carbapenemase-producing Enterobacteriaceae (CPE) at HUS.

7 to 15% of patients colonized with EPC would develop an infection with EPC. The cohorts published mainly concern patients hospitalized in intensive care. The associated mortality reported in the literature is high (> 25%) and greater than that associated with infection with the same bacterium sensitive to carbapenems.

Enrollment: 274 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Major subject (≥18 years old)
• Subject hospitalized at HUS between 01/01/2011 and 07/31/2021
• Clinical sample or rectal screening smear finding an enterobacterium producing a carbapenemase (EPC)
• Subject not having expressed their opposition to participating in the study

Exclusion criteria

• Subject having expressed opposition to participating in the study
• Subject under guardianship or guardianship
• Subject under safeguard of justice