Infectious Agents Exposure : Archiving in Dental Plaque (DIAS)

Regional University Hospital Center (CHRU)

Status: Unknown

Conditions: Infection; Dental Calculus

Study type: Observational

Funder types: Other

Identifiers

NCT03864952

29BRC18.0131 (DIAS study)

Details and patient eligibility

About

We are studying the possibility of using dental calculus as a reservoir for the genes of an infectious agent that has infected the patient in previous months; as it is done to highlight climate change in ice samples.

Full description

From a sample of people who have had a microbiologically well-documented infection, we will study the possibility after genomic amplification to find, three to 12 months after genetic sequences of the infectious agent in the dental calculus of the person. The people will be recruited according to a large panel of infectious agent (gram + and gram bacterium, mycobacteria, parasite, fungus, DNA, RNA or retrovirus) and, of course, the presence of dental calculus.

Enrollment: 15 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• three months before, having been infected with a documented pathogen
• this infection must have been clinically obvious
• the patient must have dental calculus

Exclusion criteria

• to be under 18 years old
• to be incapable to consenting
• a tartar removal since the infection