Infectious Outcomes Following Pancreas Transplantation

University of Pittsburgh

Status: Completed

Conditions: Pancreatic Transplantation

Study type: Observational

Funder types: Other

Identifiers

NCT00332111

IRB# 0603103

Details and patient eligibility

About

The proposed protocol aims to characterize the infectious episodes in pancreas transplant recipients under the current medical care. Knowing these patients infectious risks, the types of infections that commonly affect them and the morbidity and mortality associated with it will provide valuable information in the evaluation of the safety and efficacy of the current practices. The information generated by this study will also serve as the basis for development of strategies targeting prophylaxis of infectious episodes.

Full description

The objectives of the study are:

1. To determine what is the frequency of infectious complications following pancreas transplantation
2. Characterize the clinical and microbiological aspects of the infectious complications following pancreas transplantation
3. Identify predictors for infection following pancreas transplantation
4. Determine the frequency of graft loss and associated mortality of infectious complications following pancreas transplantation

Enrollment: 300 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who underwent pancreas with or without kidney transplantation at the University of Pittsburgh Medical Center from January 1st 2002 to December 31st 2005
• Patients must be above 18 years of age
• Patients undergoing retransplantation may be included.

Exclusion criteria

• History of pancreas transplantation at another institution