Infective Endocarditis in Developing Countries, a Prospective, Observational, Multicentre Study (EndoDev)

Institut National de la Santé Et de la Recherche Médicale, France

Status: Completed

Conditions: Infective Endocarditis

Study type: Observational

Funder types: Other; Other U.S. Federal agency

Identifiers

NCT02128139

C12-37 / EndoDev

Cardiology and Development (Other Identifier)

Details and patient eligibility

About

Introduction. Comprehensive data on infective endocarditis in developing countries are scarce.

Objectives: Description of the characteristics (clinical and microbiological) and assessment of the outcomes of infective endocarditis in low-income countries.

Methods : Prospective, Observational, Multicentre study. Inclusion criteria: patients aged over 1 year fulfilling the modified Duke criteria for infective endocarditis.

Exclusion criteria: patient included during a previous infective endocarditis episode.

Outcomes measures: Mortality at 6 months follow-up; mortality at 1 month follow-up; access to antibiotic treatment (modalities and duration), hospital length of stay and reason for discharge, and cardiac surgery when indicated.

Duration: One year (June 2014- June 2015)

Enrollment: 300 patients

Sex: All

Ages: 1+ year old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged over 1 year diagnosed with infective endocarditis according to the modified Duke criteria

Exclusion criteria

• Already included for a previous episode of infective endocarditis (i.e., relapse or reinfection)