Inferior Oblique Muscle Anteriorization Versus Anteriorization and Resection in DVD With IOOA

Kasr El Aini Hospital

Status: Completed

Conditions: Dissociated Vertical Deviation; Inferior Oblique Overaction

Treatments: Procedure: Inferior oblique anteriorization; Procedure: Inferior oblique anteriorization together with unliateral resction

Study type: Interventional

Funder types: Other

Identifiers

NCT05980962

N-97-2018

Details and patient eligibility

About

The goal of this clinical trial is to compare the results of two surgical modalities in patients with Dissociated vertical deviation with inferior oblique muscle overaction . The main questions it aims to answer are:

• How much does the magnitude of DVD improve after each modality?
• Is the IOOA eliminated? Participants will be divided into two equal groups; Researchers will compare the efficacy of symmetrical anteriorization of the inferior oblique and adding an additional rescetion to one eye in the second group to see which group had more signifcant reduction in the magnitude of DVD and IOOA.

Full description

A prospective study was performed on patients with bilateral symmterical dissociated vertical deviation(DVD) and bilateral inferior oblique muscle overaction (IOOA) in Cairo University hospitals starting from February 2018 through December 2021. Patients wetre included in the study if they had a minimum follow up period of 6 months. The study included 54 patients (108 eyes) with manifest DVD and IOOA in boths eyes. Patients were divided into two equal groups. The paitents in group 1 underwent symmetrical inferior oblique muscle anteriorization, while the patients in group 2 underwent ayymmetrical surgery , where inferior oblique anteriorization was performed in one eye the same manner is in group 1, and the eye with the larger deviation had an additional 3-5 mm rescetion of the inferior oblique muscle along with anteriorization according to the measured DVD difference between both eyes, whether less than or more than 5 prism diopters respectively.

Enrollment: 54 patients

Sex: All

Ages: 1+ year old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Manifest DVD decompensated to a tropia with free ocular motility
• Cases with or without horizontal misalignment
• Cases with or without previous horizontal muscle surgery

Exclusion criteria

• Incomitant, Paralytic or restrictive strabismus
• Eyes with previous inferior oblique muscle surgery
• Recurrent DVD after surgical treatment
• Eyes with previous scleral buckling for retinal deatchment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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54 participants in 2 patient groups

Group 1 (Anteriorization group)

Active Comparator group

Description:

Symmetrical Anteriorization of the inferior oblique muscle

Treatment:

Procedure: Inferior oblique anteriorization

Group 2 (Resction group)

Experimental group

Description:

Asymmetrical Anteriorization of the inferior oblique muscle, where an additional resection of the inferior oblique was done for the eye with the larger deviation

Treatment:

Procedure: Inferior oblique anteriorization together with unliateral resction