Infertility and Pregnancy Outcomes of Fertility Spared Gynecological Oncology Patients

Acibadem University

Status: Enrolling

Conditions: Fertility Disorders; Gynecologic Cancer

Treatments: Procedure: Fertility sparing surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT05823194

2022-17/10

Details and patient eligibility

About

FSS which aims to preserve a woman's fertility while still effectively treating the cancer, has become an increasingly popular option for young women diagnosed with these types of cancers. It is important to assess how FSS affects a woman's reproductive health, sexual function, psychological well-being, and overall quality of life. This research aims to provide valuable insights into the long-term effects of FSS on a woman's life, and can help healthcare providers make informed decisions about the best treatment options for their patients.

Full description

This is a prospective cohort study that aims to evaluate the infertility and pregnancy outcomes, as well as the quality of life of women who underwent fertility-sparing surgery for gynecological malignancies. The study included a comprehensive evaluation of the participants' medical history, surgical procedures, oncological treatment, and fertility preservation methods. Participants recruited from a tertiary care hospital, and women diagnosed with gynecological malignancies (e.g. cervical, ovarian, endometrial cancer) who underwent fertility-sparing surgery between 2010 and 2022. Women who have undergone total hysterectomy, bilateral salpingo-oophorectomy, or adjuvant oncological treatment were excluded from the study. Participants were contacted by phone and asked to complete questionnaires to assess their quality of life using the WHOQoL-BREF and FertiQoL scales.

Enrollment: 50 estimated patients

Sex: Female

Ages: 20 to 49 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of gynecologic cancer, and being fertile in the meantime
• Applying directly to gynecologic oncology department
• Demand of preserving the fertility

Exclusion criteria

• Having hysterectomy prior to the diagnosis
• Having bilateral ooferectomy prior to the diagnosis
• Being in menopause
• Not accepting to fill the survey
• High stage disease which is not able to have FSS

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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50 participants in 1 patient group

Fertility spared gynecologic cancer diagnosed women

Other group

Description:

Participants recruited from a tertiary care hospital, and women diagnosed with gynecological malignancies (e.g. cervical, ovarian, endometrial cancer) who underwent fertility-sparing surgery between 2010 and 2022.

Treatment:

Procedure: Fertility sparing surgery