Inflammation as a Predictor in Cardioversion of Atrial Fibrillation

Creighton University

Status: Completed

Conditions: Atrial Fibrillation

Treatments: Procedure: Cardioversion

Study type: Observational

Funder types: Other

Identifiers

NCT00590525

04-13547

Details and patient eligibility

About

The laboratory test, C-Reactive Protein (CRP), has become well established as a marker of inflammation. Recently a high CRP level (indicating an increase in inflammation) was identified as a risk factor for atrial fibrillation. We are conducting this study with patients such as yourself with atrial fibrillation who are planning to undergo cardioversion to determine what sort of relationship exists between CRP levels and atrial fibrillation. We will then look at success rates of converting atrial fibrillation to normal sinus rhythm, compared to patients' CRP levels.

Enrollment: 45 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

• Atrial fibrillation patients referred for DC cardioversion
• On stable medical therapy

Exclusion Criteria

• Known chronic inflammatory states such as infections, rheumatoid arthritis or known vasculitides.
• Patients having undergone recent surgery or who are on steroid therapy for any reason will be excluded.

Trial design

45 participants in 1 patient group

1

Treatment:

Procedure: Cardioversion