Inflammatory Bowel Disease(IBD)Database

Tel Aviv Sourasky Medical Center

Status: Not yet enrolling

Conditions: Inflammatory Bowel Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01266538

TASMC-10-ID-467-CTIL

Details and patient eligibility

About

This will be a comprehensive epidemiological, clinical, endoscopic and histological database for inflammatory bowel diseases patients in our medical center that will further provide clinical and basic investigations.

Full description

Inflammatory bowel diseases (IBD), which include Crohn's disease (CD), ulcerative colitis (UC), undefined IBD and pouchitis (in patients who required IPAA for their colitis) affects about two million people in the world. At this time there is no definitive cure and current treatment is aimed at managing the symptoms and inflammation that accompany these diseases. These diseases are predominantly chronic, and patients may experience various gastrointestinal symptoms depending on the location, nature, and extent of their disease. Both genetic and environmental factors play etiological roles. The overall goal of our research is to understand the etiology and course of these diseases in order to prevent and to manage cases more effectively. In order to do so we are aiming at building a comprehensive database that will include detailed clinical data conjoined with dedicated research information and collection of biological specimens that will target the gut epithelium immune system, the microbiota and specific genetic risk factors.

Enrollment: 2,500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Diagnosis of IBD Regular treatment and follow up in Tel Aviv Sourasky medical center Fap (familial polyposis)patients after a large bowel resection, as controls Family members of IBD patients as controls Patients with Irritable Bowel Syndrome (IBS), as controls -

Exclusion criteria

pregnancy age<18 years

Trial design

2,500 participants in 3 patient groups

IBD patients

Description:

Patients diagnosed with Inflammatory Bowel Disease (IBD)

patients after a Large Bowel Resection

Description:

Patients after a Large Bowel Resection, with or without a pouch.

Control group

Description:

Family members of IBD patients, Patients with Irritable Bowel Syndrome (IBS), Fap (familial polyposis)patients after a large bowel resection, Patient performing screening endoscopy