Inflammatory Responses After CrossFit and Resistance Trainings in Untrained Subjects

Habil Hamdouni

Status: Completed

Conditions: Inflammation; Plasma Volume; Hormones; Oxidative Stress

Treatments: Behavioral: 12 week training

Study type: Interventional

Funder types: Other

Identifiers

NCT07190924

ISS-1386

Details and patient eligibility

About

Considering the remarkable increase of the fitness programs, the purpose of this study was to assess and compare the effect of Crossfit (CF) and periodized resistance (RT) trainings on inflammatory/oxidative responses in untrained individuals.

Twenty-four participants (20 men and 4 women, age= 25.7 ± 2.2 years, BMI= 25.7 kg.m-2) were randomly assigned into 12 weeks of these trainings with a rate of five sessions/week. Before and after intervention, participants anthropometric data and graded exercise tests were performed. Before (pre), immediately after (post) and 60min after test (p60) a 20mL venous blood sample were drawn for a later measure of c-reactive protein (CRP), interleukin 1 beta (IL-1ß), tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), interleukin 10 (IL-10), thiobarbituric acid reactive substances (TBARS), antioxidant enzymes catalase (CAT) and glutathione peroxidase (GPx).

Enrollment: 24 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Participants must be non-smokers,
• Participants should not suffer from respiratory issues
• Participants should have healthy kidney and liver
• Participants have no metabolic and neurological disorders

Exclusion criteria

• The use of medications during the previous 4 weeks
• Consumption of any product related to anti-inflammatory/oxidative supplements

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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24 participants in 2 patient groups

CrossFit

Experimental group

Description:

High intensity functional training

Treatment:

Behavioral: 12 week training

Behavioral: 12 week training

Resistance

Experimental group

Description:

Periodized resistance training

Treatment:

Behavioral: 12 week training

Behavioral: 12 week training