Influence Instillation Plasma Rich in Growth Factors in Endometrial Cavity Endometrial Development in Assisted Reproduction.

IVI Bilbao

Status and phase: Terminated; Phase 3

Conditions: Endometrial Development

Treatments: Drug: Growth Factor, Platelet-Derived

Study type: Interventional

Funder types: Other

Identifiers

NCT02996760

1404-BIO-019-MF

Details and patient eligibility

About

Women in assisted reproduction treatment they receive own or donated embryos and presenting an endometrial development less than 5 mm despite having received treatment with estrogen therapy knowing the clinical value of using the PRGF-Endoret therapy and endometrial level applications to improve endometrial thickness endometrial preparations for embryo transfer.

Enrollment: 22 patients

Sex: Female

Ages: 18 to 49 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women receiving cycle of oocytes outside or embryos (own / others), in the treatment of substituted cycle type.
• Less than 5mm despite 10 days with standard doses of estrogen therapy (6mg / 24h) Endometrio

Exclusion criteria

• History of pelvic inflammatory disease
• Risk of infection

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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22 participants in 2 patient groups

Endometrium with less than 5mm

Experimental group

Description:

Women receiving cycle of oocytes outside or embryos (own / others), in the treatment of substituted cycle type. Less than 5mm despite 10 days with standard doses of estrogen

Treatment:

Drug: Growth Factor, Platelet-Derived

Endometrium with more than 5mm

No Intervention group

Description:

Women receiving cycle of oocytes outside or embryos (own / others), in the treatment of substituted cycle type. More than 5mm despite 10 days with standard doses of estrogen