Influence of Acupuncture to Ocular Microcirculation in Patients With Diabetes Mellitus

Technische Universität Dresden

Status and phase: Unknown; Phase 2

Conditions: Diabetes Mellitus, Type 2

Treatments: Procedure: acupuncture

Study type: Interventional

Funder types: Other

Identifiers

NCT01022177

AcuDiab1

Details and patient eligibility

About

The purpose of this study is to determine the influence of specific eye acupuncture to the ocular microcirculation in diabetic and healthy subjects.

Full description

Diabetes is combined with severe vascular damage at the different stages of the disease, causing reduction in retinal perfusion. Acupuncture is supposed to regulate the perfusion. We propose a study to evaluate the effect of acupuncture to the vascular auto regulation in patient with Diabetes, compared to healthy people without vascular or retinal diseases. The perfusion of the retinal vessel will be examined by Retinal vessel analyzer (RVA), Heidelberg retinal Flowmeter (HRF) and the Ocular blood Flowmeter (OBF) before, during and after standardized specific acupuncture at healthy volunteers and patients with diabetes.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• persons over 18 years, men or women, diabetic diagnostics within the last year

Exclusion criteria

• medical use of anticoagulative substances, use of dorzolamide, use of immunosuppressive medication
• psychiatrics, epileptics

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

40 participants in 2 patient groups

diabetics

Active Comparator group

Description:

subjects with HbA1c \>7,0 and pathological glucose tolerance testing

Treatment:

Procedure: acupuncture

healthy

Active Comparator group

Description:

healthy subjects with HbA1c \<7,0 and negative glucose tolerance testing

Treatment:

Procedure: acupuncture