Influence of Ambient Temperature on Resting Energy Expenditure of Healthy Adults

University of Bonn

Status: Completed

Conditions: Resting Energy Expenditure

Treatments: Other: Respiratory analysis at cold temperature; Other: Respiratory analysis at hot temperature; Other: Respiratory analysis at room temperature; Other: Respiratory analysis at thermoneutral temperature

Study type: Interventional

Funder types: Other

Identifiers

NCT05505240

TempRMR

Details and patient eligibility

About

The aim of this study is to investigate the influence of four different ambient temperatures (18, 22, 28, 38°C) on the resting energy expenditure of healthy adults by respiratory gas analysis. It is assumed that the resting energy expenditure is higher at 18°C and 38°C than at the temperatures in between.

Full description

In a crossover-design, 32 healthy men and women participate in four interventions. Each intervention includes a measurement of the resting energy expenditure by respiratory gas analysis at a different ambient temperature (18,22, 28 and 38°C). During this time body core- and surface temperature are assessed, as well as body composition via bioelectrical impedance analysis. For each participant the four individual study days take place in a randomized order on consecutive weekdays within a week.

Enrollment: 32 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

• BMI: 18,5 - 24,9 kg/m2
• metabolically healthy

Exclusion Criteria

• smoking
• low or high blood pressure
• dyslipidemia
• insulin resistance or diabetes mellitus type 1 or type 2
• gastrointestinal diseases (e.g. food intolerances or allergies)
• liver, kidney and/or thyroid diseases
• hepatitis B or C, HIV Infection
• chronic inflammatory diseases
• disordered eating
• psychological diseases
• alcohol and/or drug abuse
• use of medication
• pregnancy or lactating
• participation in another intervention study
• women: irregular menstrual cycle
• more than 6 h of sports per week

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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32 participants in 4 patient groups

Cold temperature

Experimental group

Description:

18°C

Treatment:

Other: Respiratory analysis at cold temperature

Room temperature

Experimental group

Description:

22°C

Treatment:

Other: Respiratory analysis at room temperature

Thermoneutral temperature

Experimental group

Description:

28°C

Treatment:

Other: Respiratory analysis at thermoneutral temperature

Hot temperature

Experimental group

Description:

38°C

Treatment:

Other: Respiratory analysis at hot temperature