Influence of Coffee Intake on Postoperative Bowel Function After Comprehensive Staging Surgery for Gynecological Malignancies: A Randomized Controlled Trial.

Erzincan Military Hospital

Status: Completed

Conditions: Ilues

Treatments: Dietary Supplement: Water; Dietary Supplement: caffe

Study type: Interventional

Funder types: Other

Identifiers

NCT01990482

gungorduk15

Details and patient eligibility

About

A delay in the return of normal bowel function with the passage of flatus and feces is one of the most important factors affecting early recovery and discharge in patients undergoing open complete staging surgery for gynecological malignancies. A prolonged hospital stay increases the risk of hospital-acquired infections, deep vein thrombosis, pulmonary compromise and total hospital costs.

The aim of this study was to assess the effectiveness of coffee intake on postoperative bowel function in patients undergoing abdominal complete staging surgery for gynecological malignancies.

Enrollment: 118 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Female patients preparing for complete surgical staging for malignant gynecologic disease such as endometrial cancer, cervix cancer and ovarian cancerwere assessed for eligibility. Exclusion Criteria: Exclusion criteria for the study
• included thyroid diseases,
• inflammatory bowel disease,
• complaints of chronic constipation (defined as two or fewer bowel movements per week),
• a history of prior abdominal bowel surgery, abdominal radiation, neoadjuvant chemotherapy,
• need for intensive care more that 24 hpostoperatively,
• nasogastric tube drainage beyond the first postoperative morning,
• bowel anastomosis and upper abdominalmultivisceral surgical approaches in relation to the debulking surgery.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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118 participants in 2 patient groups, including a placebo group

coffee

Experimental group

Description:

coffee

Treatment:

Dietary Supplement: Water

Dietary Supplement: caffe

water group

Placebo Comparator group

Description:

water

Treatment:

Dietary Supplement: Water

Dietary Supplement: caffe