Influence of Daylong Glycemia on Detraining Induced Metabolic Changes

University of Hohenheim

Status: Completed

Conditions: Healthy

Treatments: Dietary Supplement: soft drinks

Study type: Interventional

Funder types: Other

Identifiers

NCT02321033

Lazysportsmen2014

Details and patient eligibility

About

Aim of the study is to investigate the impact of glycemic index (provided as soft drinks) on changes in insulin sensitivity, metabolic flexibility, and arterial stiffness in response to detraining.

The investigators hypothesize that low glycemic soft drinks decrease the detraining-induced impairment of insulin sensitivity, metabolic flexibility and arterial stiffness.

Full description

The duration of the study is 7 weeks: two x 2 weeks intervention (phase A and phase B) with 3 weeks washout phase inbetween. Each 2-week intervention phase consists of an active week followed by an inactive week.

in phase A subjects consume high GI (maltodextrin and sucrose) soft drinks during the inactive week. In phase B subjects consume a low GI soft drink (palatinose) during the inactive week.

subjects were randomly assigned to either start with phase A or with phase B (cross over design).

During the whole study duration all food is provided (55% CHO, 30% fat, 15% protein)

Physical activity will be assessed by a step counter (active phase 7000-10000 steps/d and inactive phase 3000-4000 steps/d).

Enrollment: 16 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• normal weight men,
• age 18-35 y,
• active life style,
• > 300 min sports/week

Exclusion criteria

• food allergies,
• regular use of medication,
• smoking,
• chronic disease,
• vegan/vegetarian diet

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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16 participants in 2 patient groups

low glycemic index

Experimental group

Description:

palatinose in soft drinks

Treatment:

Dietary Supplement: soft drinks

high glycemic index

Experimental group

Description:

sucrose plus maltodextrin in soft drinks

Treatment:

Dietary Supplement: soft drinks