Influence of Early Standing Training on ICU Patients

Chinese PLA General Hospital (301 Hospital)

Status: Unknown

Conditions: Pulmonary Disease

Treatments: Behavioral: Intensive rehabilitation

Study type: Interventional

Funder types: Other

Identifiers

NCT04460391

Intensive rehabilitation

Details and patient eligibility

About

Influence of early standing training on ICU patients

Full description

Objective: To study the effect of early standing training on ICU patients.Background: Early severe rehabilitation is of great significance for patients, which can help patients withdraw from mechanical ventilation as soon as possible, improve pulmonary ventilation, and promote early walking.However, patients on mechanical ventilation are more prone to delirium, muscle weakness, ventilator dependence and other problems. Early standing training can significantly improve patients' lower limb muscle strength, improve diaphragm function, improve the prognosis of patients, and reduce the length of hospital stay.Methods: selecting stable hemodynamics in ICU patients with mechanical ventilation, randomly divided into two groups, a group of routine rehabilitation training, another group stand for regular rehabilitation and early training, with the aid of electric beds, on the first day of patients, to evaluate the seventh day, the 14th day, and collect the basic information for patients and strength assessment, blood gas analysis, the diaphragm of the bed and ultrasound and muscle ultrasound, and record the patient's mortality within 28 days, the incidence of delirium, decannulation rate, etc., recorded in patients with mechanical ventilation time and the time required to walk independently and ICU stay time.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The age is ≥ 18 years old;
• the hemodynamics is stable;
• 50 < heart rate < 120 beats / min ;
• 90 < systolic blood pressure < 200mmHg ;
• 55 < mean arterial pressure < 120mmHg;
• do not increase the dose of pressor drugs for at least 2 hours;
• intracranial pressure is stable and there are no seizures within 24 hours;
• the respiratory state is stable;
• the patient's finger pulse oxygen saturation ≥ 88%;
• Oxygen concentration less than 60%；
• Terminal positive expiratory pressure<12cmH2O；
• 10 < respiratory frequency < 35 beats / min.

Exclusion criteria

• Pregnancy;
• acute cardio-cerebrovascular events;
• spinal or limb fractures;
• active bleeding.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups

experimental group

Experimental group

Description:

Early standing training and routine rehabilitation

Treatment:

Behavioral: Intensive rehabilitation

control group

Active Comparator group

Description:

Conventional rehabilitation，Muscle training and breathing training

Treatment:

Behavioral: Intensive rehabilitation