Influence of Environmental Factors on the Efficacy of Non-surgical Periodontal Treatment. A Pre-post Quasi-experimental Study

University of Siena

Status: Unknown

Conditions: Periodontitis; Periodontal Diseases; Non Surgical Periodontal Treatment

Treatments: Other: Questionnaires; Procedure: Non-surgical periodontal treatment

Study type: Observational

Funder types: Other

Identifiers

NCT04769622

NST001

Details and patient eligibility

About

Periodontitis is a biofilm-mediated chronic inflammatory disease which causes the destruction of the supporting tissues of the tooth. Risk factors for periodontitis include familiarity for periodontal diseases, diabetes, cardiovascular diseases, metabolic syndrome, obesity and stress. Some studies demonstrated how these risk factors negatively influence the patients' response to non-surgical periodontal treatment. The success of non-surgical periodontal therapy is defined through the treat-to-target concept (i.e. a maximum of 4 sites with Probing Pocket Depth >5mm and presence of Bleeding on Probing); therefore, periodontal treatment is successful whenever this threshold is reached. Moreover, given the available data regarding the association between more severe forms of periodontitis and a lower frequency of physical activity, a worse sleep quality and more perceived stress, it is reasonable to hypothesize that these factors could influence the patients' response to non-surgical periodontal treatment. With regards to diet, despite many studies appraised the anti-inflammatory effect of the mediterranean diet, no study has ever related adherence to Mediterranean Diet to oral health status. The novelty that the present study would introduce is the evaluation of how environmental factors (i.e. diet, physical exercise, perceived stress) influence patients' response to non-surgical periodontal therapy.

Enrollment: 125 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age between 18 and 70 years old;
• presence of untreated periodontitis (Papapanou at al. 2018);
• ability and willingness to give informed consent.

Exclusion criteria

• pregnancy or lactation;
• patients who underwent non-surgical periodontal therapy in the last 6 months;
• patients taking immunosuppressive drugs;
• inability or unwillingness to give informed consent.

Trial design

125 participants in 1 patient group

patients affected by untreated Periodontitis

Description:

patients coming to the Unit of Periodontics at the University of Siena will be screened for the inclusion in the study. All patients eligible for the inclusion in the study will undergo non-surgical periodontal treatment and will be administered a questionnaire about lifestyles (adherence to mediterranean diet, sleep quality, physical activity, perceived stress). Patients will be then reevaluated at 3 months after the completion on non-surgical periodontal therapy.

Treatment:

Procedure: Non-surgical periodontal treatment

Other: Questionnaires